Is this server in a cluster? I'm having a similar issue.
It seems i have found the solutions at least for my problem but here is my solution.
Path : C:\Program Files (x86)\McAfee\ePolicy Orchestrator\DB\server.ini
In SERVER.INI :
Add a line at the bottom
change 10.0.0.x for your server Ip Adress
I found that for EPO 3.x and i tried it and it worked.Hope it's helpful for you
Thank you very much for your input, however could you please advise if you need to restart services or something like that after editing that file ?
Yes, you'll need to restart the ePO services after modifying server.ini.