Sorry, I'm not sure what the question is - can you clarify?
you have a rather complex question :-)
The issue you are referring to here applies to McAfee Agent 4.5 when a series of concurrent conditions all are being present. As per the article you quote here, you must have all those software installed and working to have the chance of the issue occurring described in the article.
If you experience the issue and you all have the software listed as root cause, the you better install the hotfix as well. If you do not have all the software listed installed, you need not install the MA hotfix, as it only fixes the issue occurring when all those software listed are installed.
As for VSE 8.7 Repost Patch 3, it has the McAfee Agent 184.108.40.2066, so this (i.e VSE package itself) might not be affected by the issue described in the article. If you however install McAfee Agent 4.5 after you have installed VSE 8.7 Repost Patch 3, you could have the issue under the conditions described in the article. In that case you simply install the MA hotfix.