Have you considered uninstalling McAfee to see if it makes a difference? Or going through the settings and basically disabling it, then turning things on one at a time until you hopefully find the culprit?
Yes, I forgot to add.
The settings were actually greyed out and I hadn't told ePolicy about the server nor did it add itself in. We are going to uninstall but this was my last gasp just prior to uninstalling in case somebody had experienced it prior and would have an alternate work around. Thanks Andy and I'll let you know.