Maybe Sql server services stopped. You should try start SQL Server Service or check here for more info https://kc.mcafee.com/corporate/index?page=content&id=KB51660
but my SQL server is on another server and not on the same server with the epo...and the sql doesn't have any problems....
Please post the Orion.log - it would possibly contain more detail...
Orion.log can be found under ePolicy Orchestrator\Server\Logs folder