There was a topic that encrypting whole disk space could potentially trigger sector reallocation on marginal drives. Check those disk drives extensively for any IO errors (full surface scan when disk is encrypted).
SMART data reports no failure predicted and Scan Disk going through all phases gives the HDD a thumbs up as well.
Decrypting a subset of the users immediately resolved the problem. Uh oh...
FWIW, some of these databases are 8GB+, any issues anyone has run into handling file sizes this large with EEPC installed?
Use performance monitor on those PC's. Compare disk access performance on encrypted and non-encrypted machines (Disk % idle time). I know that specific disk IO benchmark tests show very significant performance reduction with encryption turned on. So if disk access is very heavy (like local database operations), overall performance could be affected tremendeously.
Just want to report we have a large environment, roughly 38,000 laptops, running EEPC 5.1.8, corporate groupware/email is Lotus Notes R7 and R8. No issues like this reported so far. HP hardware shop.