From what you've posted, it seems like a set of preset settings are being enforced and thus overwriting the changes you make.
How was the McAfee installed, and where did you get the installer from? At first glance, I would associate that behaviour with a managed install of VSE (Ie an Administrator has given you the package to install, and they control it via E-Policy Orchestrator).
It is indeed an admin that installed mcafee on my machine.Though, I am never connected to the original network... so I don't think it's related.
You do not have to be connected to the network for policy enforcement to occur.
The policies are already on your system. Every time you change them, they get reinforced again at the next policy enforcement interval.
The default interval is 5 minutes.
Those policies are for your own protection, at least your administrator feels that way, so you shouldn't be changing them.
Of course if you disagree, it is your admin you need to speak with. We wouldn't want to help you circumvent your companies security policies