Moving this thread to the SecurityCenter space...
Does McAfee still asks you to restart the computer, Even after you restart your computer ?
If so you can try a few steps
- Right-click Start and select Explore.
- Navigate to the appropriate location below:
Windows XP: C:\Documents and Settings\All Users\Start Menu\Programs\Startup\
Windows Vista and 7: C:\ProgramData\Start Menu\Programs\Startup
- Locate and delete a file similar to this example: $McRebootA5E6DEAA56$.
NOTE: This filename varies, the numbers after $McReboot will be slightly different.
- Restart your computer.
Else it is advisable to Reinstall you McAfee software from McAfee website.
Are you still facing trouble opening security center , if so kindly report back so that we could help you.