PITool, what's that? What version of McAfee are you talking about and how are you installing it and where exactly is this red X appearing?
Also exactly what version of Vista is this?
Also can you please advise what version of IE8 you are using. Is it the final version?
I'm Installing McAfee Total Protection online from McAfee Account.
The Download Manager downloads all the information around 63MB + 32 MB of data , When it comes to the final stage of McAfee installation where it installs all the components like Virus scan, Firewall , Anti spam etc.. Got a RED X on all the components.
Version of OS is Windows Vista Ultimate ( Build 6000) .
Well first it should be Vista SP2 which I believe yours is not.
Secondly what version of Internet Explorer is installed? You should be using IE8 final version at its default settings.
If you've already ascertained that no other protection software is present nor any malware then I can only assume that it is failing because aspects of Windows aren't the latest.
You could check with Technical Support Chat (free) who can link directly with your machine to check this out.
Under McAfee Support at the top of this page you will see Home and Home Office Support, click that and then Technical Support.
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Also check this document: http://service.mcafee.com/faqdocument.aspx?id=TS100299&lang=en_US&prior_tid=2&An swerID=16777216&turl==http%3A%2F%2Fkb.mcafee.com%2Finfocenter%2Findex%3Fpage%3Dc ontent%26id%3DTS100299%26actp%3Dsearch