Moved to VSE Community.
Which version of VSE, and which Notes version?
I'm not aware of an easy way to uninstall the Lotus Notes plugin via EPO (although you can certainly disable it there. Doesn't uninstall it though).
Perhaps use Installation Designer to make a new Installation package with On-Delivery Email scanning not installed, check that into EPO and then uninstall VSE on all desktops, and deploy the new version might be a convoluted but workable way.
Otherwise, there is a command (or set of commands) you can run on the desktops to uninstall only the Lotus Notes scanning in VSE.
While I've never used the Lotus Notes Email scanning functionality in VSE because I didn't really trust it (and the interaction with Notes), it has gotten better in VSE 8.5 / 8.7 and I am surprised you are having so many dramas.
Depending on how the Domino domain is set up, there may be a way in domino to force the clients to remove the 'offending' lines in notes.ini that load the McAfee plugin. I know you can add in new lines to the Notes.ini, but can't recall if you can remove them.
Thanks for your reply. VSE version is 8.5/ePO 4.0 orchestrator patch 5 and Notes version is also 8.5
Also, I did not mention anything about uninstalling in my post, all I wanted is to disable the on-delivery e-mail scanner stopping notes clients loading from people worstation, nothing to do with uninstall (I am not uninstalling)
I have been able to create a policy to disabled the on-delivery e-mail scanner, tested and working fine.(950 machines)
Many thanks to you all
Policy created and working ok