The McAfee Agent has 2 modes of operation: Agent and Updater. The latter is a subset of the former.
If you do not have an Agent when you install VSE, then VSE will install an Updater.
In other words, you don't need the McAfee Agent
Followup question, if you have unmanaged VirusScan 8.5i & 8.7i clients, how do you keep the Updater portion up to date and current with patches? Are VSE patches such as 8.5i Patch 8 and 8.7i Patch 2 include the latest Updater files, or do these need to be maintained seperatly via Framework 3.x or 4.x patches?
I believe you already know but were just looking for confirmation...
Issues with the Updater portion of the Agent, for unmanaged systems, will need to be patched with the Agent patches too.
The same package can be used for managed or unmanaged systems.