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XP SP3 I hope? Check that your system clock is accurate.
First, enable Windows Firewall to provide you some protection.
Check for spyware/,alware using the free version of these two tools, update them before running and let them remove anything they find.
If that fails then try running the MCPR removal tool linked in my signature & reboot and retry.
If it indicates that it was unsuccessful run it again and reboot then retry.
Another thing that sometimes helps, assuming you have either IE7 or 8 installed (you should have 8 even if you don't use it) - go to IE Tools/Internet Options/Advanced and click the Reset button. OK any prompts and click Apply and OK.
Close and reopen IE and go to Tools/Manage Add-Ons and re-enable the add-ons.
McAfee relies on an up to date IE working at its default settings even if it's not your default browser.