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If it really is VirusScan 10 we're talking about then it isn't surprising as it's obsolete.
Please include the following information:
What is your operating system, service pack and are you up to date with Microsoft update?
What McAfee products do you have? If your taskbar icon is like this: - right-click it and go to each application "About" and post the details.
If it is like this: - double-click to open SecurityCenter and then click "View Details" or "About" at the lower right of the new window. Post the details from each module.
IE7 does not have any problems with McAfee and vice versa. IE8 beta does, however.
Please reinstall IE7 to be securer.
Please post the information I've asked for, thanks.
Also when you say Security Center wont open, do you mean it wont open at all, or it opens blank?
Do you have any other protection software installed?
Check for spyware using the free version of this tool: http://www.superantispyware.com/superantispywarefreevspro.html
Go to I.E. Tools/Internet Options/Security make sure each zone is set to default. Do the same for the Advanced tab.
Go to the Content tab and ensure that Content Advisor is turned off.
Do the following:
1. Uninstall all McAfee programs through "Add or Remove Programs" in Windows "Control Panel".
2. Use the MCPR tool, see this article: How to remove supported McAfee consumer products using the McAfee Consumer Products Removal tool (MCPR.exe). This will remove all McAfee remnants from your computer. (you must have Windows Vista, XP or 2000 SP4 to use this tool)
3. Launch Windows Explorer and delete all McAfee files in "Program Files" but especially in "C:\Document and Settings\<user>\Application Data" and "C:\Document and Settings\All Users\Application Data". You have to set Windows Explorer to show all hidden files and folders (Tools > Folder Options > View tab). Just delete the McAfee folders even if they are empty in all the "Application Data" folders. Can be more than one!
In Vista: C:\Program Files, C:\ProgramData and C:\Users\yourname\AppData\Roaming
4. Reboot and redownload/reinstall your McAfee products directly from your account at the McAfee web site, NOT from any CD that you may have.