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McAfee won't allow you to keep what it detects, even if it is a false positive.
Regarding false positives you can send McAfee the detection/file, and they may issue you an extra.dat so it won't be detected anymore, but that's the best you can get with McAfee.
Of course, there is always the possibility that McAfee will claim that the false positive is a real infection.
On the bright side, McAfee has relatively few false positives.