I am running Livesafe. Outlook 2010, Windows 10 Pro 64 bit. Outlook will not open. Have to run in Safe Mode ans sometimes even that will not open.. Microsoft reports the problem is McAfee Add-In and asks if I want to disable it. I do and Outlook opens. However I had previosly diabled it manually from the Outlook Add-Ins menu. How did it re-enable? When I cannot open it in safe-mode, and Microsoft doesn't prompt me to disable I am stuck.
I would try running the McAfee Virtual Technician if it does not resolve the problem.McAfee Virtual Technician
I would then contact Technical support and provide the MVT Session number. Phone/Online Chat being the most expedient. McAfee Consumer Support Portal