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According to the release note for the new EPO Agent 4.5, it states the following below:
System Tray issues
When running 64-bit operating systems, some managed product icons might appear outside of the McAfee System Tray icon. (486449)
The System Tray icon might not appear on VMware systems running Windows 2008 Service Pack 2. (487483)
If it is not fixed with EPO 4.5 agent then it will still be there with EPO Agent 4.0 P3. I have just used to it in our environment.