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Detecting Encoded or non-Standard Binary Files

I am looking for a way to detect encoded (i.e. Base64) text and/or files within DLP.  I have a RegEx that generally works, but due to the way Base64 works (primarily alphanumeric characters), it detects far too many false positives.  What I am trying to accomplish is detect all or part of a message/file that is encoded and generate an incident.

Additionally, I am in search of a way to detect non-standard files.  For instance, if someone were to append encoded/binary content to the end of legitimate file type (jpeg, doc, etc.) to exfiltrate data.  

If anyone has had any success or suggestions around this, I would greatly appreciate it.

Kind Regards,


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