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Violating rule "Protect McAfee core registry keys and values" was blocked

Why Analyzer detection method "Self protection" blocking IE? This violation triggers every day and almoust in every computer. What is the best way to handle with it. I don't want to ignore this block. Is there any opportunity to do a exclusion for this rule? Under AP there isn't such a rule. Description: IEXPLORE.EXE, which tried to access HKCU\SOFTWARE\MICROSOFT\WINDOWS\CURRENTVERSION\EXT\SETTINGS\{7DB2D5A0-7241-4E79-B68D-6309F01C5231}\, violating the rule "Threat Prevention - Protect McAfee core registry keys and values", and was blocked.
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