...................and don't forget if you are running ePO 4.5 with installed Agent Handlers you'll need to uninstall the Agent Handler and then re-install with the ones contained in the Patch 1 download.
Our Agent Handlers reported they were incompatible with ePO 4.5 Patch 1 and we were unable to just re-run the setup to upgrade the Agent Handler as it kept prompting us for another disk! We had to de-install and re-install.
Hmm, that's not right - you certainly should be able to upgrade the agent handlers. I've just done a quick test without any problems...
I'm not sure why you had this problem
I must confess I only tried the upgrade on one AH, it wasn't to much of a hassle to uninstall and re-install.
I used the same source files as the successful re-install but the upgrade just stopped and asked for Disc 1