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StorSimple and VirusScan setup?

We have a StorSimple unit and we had to remove VirusScan today because it was seriously impacting the performance, to a point that nobody could access the files on it.

From what I have been reading in other sites, Microsoft recommends not doing a full scan of the server at any time because it could affect the cloud hosted files and thus cause the performance hit that we have suffered.

Any hints how we should use VirusScan on a StorSimple?