Hi, Thanks for your reply! I should have added more detail.
We're not using the computer account, we use a domain account to access the db and that's still working fine. This only started happening when we changed the name of the DB server.
We're not using the epo server account for anything, it just started trying to connect on it's own! We're trying to figure out why the account would start doing this. It's filling the app log on the DB server because it's trying to connect every few seconds and failing.