Can you confirm all the McAfee services are running on the EPO server? Theses are the service names McAfee ePolicy Orchestrator x.x.x Application Server McAfee ePolicy Orchestrator x.x.x Server McAfee ePolicy Orchestrator x.x.x Event Parser
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What logs are filling it up? You can control the size of the logs for Orion logs in the log-config.xml file (see kb52369). If it is in debug mode also, that will create a lot of unnecessary logging and could cause performance problems.
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