You are at present running McAfee's legendary applications.They are the most basic and works well.
When it comes to new products, most of them are bought over and product management is bit dull. I would recommend you going for single agent/management solution. But please test all the products if you don't want to end up in my situation. Check OS and application compatibility especially and read the entire documentation because there are 'notes' in few of the product documentation (not in the 'read me') that may derail your implementation plan. Gold support is only good for the updates and product revisions. Check your McAfee partner's credibility. Let's hope and pray that McAfee doesn't dump you after the sale. meanwhile, I would suggest the following products:
Host IPS - mature product featurewise, requires additional coding or corrections to increase efficiency on newer os and applications.
Host Data Loss Prevention (effectiveness depends on your requirements) and excellent alternative would be http://www.cyberoam.com/dataprotection.html. Host DLP's power lies in its ability to control leakage based on content of the file. not only extensions or names.
Vulnerability Manager (careful if you have lots of DMZs. too many ports to open)
Remediation Manager (use with Vulnerability Manager)
I would stay away from:
Web Gateway - ISA with GFI web monitor is a much better and cheaper solution. considering also the maintenance cost
I would recommend using multivendors products. let's say McAfee in desktops and other vendor products in server. or separate vendors based on perimeter, extranet and intranet.
All the opinions above are personal and based on my 'experience' with the products.