In c:\programdata\mcafee\agent\logs, there is an masvc log. That will show you if the task invoked or not. In the same directory there is an mcscript log. That will tell you any problems it has downloading dats from your repositories. What version of the agent? Some of the 5.0 versions below 5.0.6 had some scheduling and dat update issues that are resolved in the higher version. However, i would recommend 5.5 agent, as 5.0.6 needs a hotfix that you have to open an SR with McAfee to obtain/
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5.0.6 has a problem with the proxy settings - if no user is logged in, but you have it to use the system proxy in the agent policies, then it will fail to download from the repository and not update, unless your logged into the machine.
You will need to either specify the proxy manually or choose No Proxy