Is it possible to allow 2 -3 GB file to be transfert but stop any AV/Malware checkup for anything over 100/200 MB? It is useless and time consuming for the user. The local AV on the workstation will take over for the big transfet.
Yes. The best way to do this is via a whitelist entry. Of course implies that the Content Length header must be present, which is generally the case