What should i do if size of the folder having quarantine files becomes too large? I mean is it safe to delete all files or something else?
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Sometimes the quarantine folder gets too large and wont empty properly when you try, it simply freezes. In which case try the following:
It's a known issue, when there are too many the deletion jams up. You can physically remove them from within the Windows environment.
First double-click the taskbar icon to open SecurityCenter
Click Navigation (top right)
Click General Settings & Alerts (left)
Click Access Protection to expand that section
Uncheck Access Protection and click Apply
Leave SecurityCenter open on your desktop because you should re-enable Access Protection after the following steps.
Go to C:\ProgramData\McAfee\VirusScan\Quarantine and click Edit/Select All
Click Shift and Delete simultaneously and the folder should empty.
Take care to delete only the contents of that folder, not the folder itself.
Re-enable Access Protection as mentioned above and click Apply and then exit SecurityCenter.
Those instructions are for Vista/Windows 7.
For XP the folder is found at: C:\Documents & Settings\All Users\Application Data\McAfee\Virusscan
You can reduce their number in future considerably if you are prepared to accept Tracking Cookies. Those enable websites to remember your sign-in details etc.
With SecurityCenter open click Virus and Spyware Protection to expand that section.
Click Real-Time Scanning
Click Settings and scroll down to Tracking Cookies
Uncheck that and click Apply.
(Note: the latest versions of SecurityCenter don't block Tracking Cookies in any case as they are deemed harmless).