Using McAfee Enterprise (ePo) VSE v8.8.
Installing Win10 1703 update, it advises McAfee must be removed. The 1703 update attempts to do this but cannot. Removing manually via Programs & Features results in error "McAfee Agent cannot be removed while it is in managed mode". Removing manually from an elevated Command Prompt using frmtinst.exe /remove=agent or frminst.exe /forceuninstall gives error "This app can't run on this PC. McAfee Agent 5 doesn't work on this version of Windows".
Windows 10 Creators Update needs Agent 5.0.5, so either update to 5.0.5 or remove. If uninstall fails, contact McAfee Support and ask for the "McAfee Removal Tool" (MFERemoval100.exe). This tool succeeds at removing a bunch of McAfee products like VSE, Agent or HIPS even if normal uninstall won't work.