Hi Shinoj ,
Thanks for your post,
Well at present, We have the only option to add the MD5 for the exe to add in VSE / ENS access protection rule to block and report.
Other MD5 value other exe process will be applicable even with VSE/ ENS access protection rule. However you can use the ENS exploit prevention expert rule to block the MD5 value like .txt .dll , lnk files as such.
I suggest you raise the PER with McAfee to check if the SHA256 or equivalent can be given as option.
Here is the link for raising PER
https://kc.mcafee.com/corporate/index?page=content&id=KB60021
Let me know if you have any further questions.