I Installed HIPS 22.214.171.1249 with Agent 4.0.01421. On a window 2003 server running Microsoft Exhange
We reboot it daily, and since HIPs has been installed the following servcice do not start:
SMTP, NNTP, FTP Publishing, HTTP SSL, Exchange IMAP4,POP3 and Routing Engine.
Seems like IIS Admin Service delays starting and this cause the other from starting.
Look in the HIPS Activity log on that server in the system tray, and look for blocks. You need to go into ePO and make exceptions for these blocked activities.