Thanks for raising your question here in the community forum,
The ENS OCT update SYSCORE does not conflict with HIPS SYSCORE,
Suggest you to check the compatibility KB of HIPS with other McAfee products.
https://kc.mcafee.com/corporate/index?page=content&id=KB70778
I suggest you to start troubleshooting from the beginning to isolate suspected component in HIPS blocking the traffic.
https://kc.mcafee.com/corporate/index?page=content&id=KB54960
We know very well HIPS works as implicit block and explicit allow, The traffic will be allowed when it matches the rule, If the rule is already in place.
Also check in local HIPS console the Firewall rule is enforced.
Put the machine in Adaptive mode (rules are learned automatically) and check if blocked traffic is allowed.
Automatically if the Adaptive mode allows the traffic then you can configure the new adaptive rule to allow the inbound traffic.
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