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Systemerrorcode 5 while updating Threat Prevention IPS v. 10.6

Dear Cummunity! Hopefully you can lend me your wisdom. This Problem accure on different machines while updating the newest Patches over EPO Server. The Machines run on Win10. The Installation start every time I try to open up an Explorer or change something on the system. What I have Done to try to solve the Issue: Try to locally disable the on access scan and grand permissions to the folder – surely not working. Uninstalled every Module of McAfee and agent and tried to reinstall. (Endpoint Security isn’t possible to uninstall) Try to Force Updates and Agent wakes over the Server and Client Again. Is there an easy way to solve this for EPO beginners? Agent Version 5.5.1.342 Drive Encryption Agent 7.2.6.6 Drive Encryption Go 7.2.5.24 Drive Encryption 7.2.6.6 Endpoint Security 10.6 Thanks and BR
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