I found that Application Specific Rule and FQDN based rule can be created with 10.6.x or higher but it is unclear if a full regex or wildcard based rules can be created for both FilePath and FQDNs.
Examples for the needs:
1. Allow/Block Rule with FilePath containing version number
/Applications/AppFolder/x.x.x.x/AppName.app
2. Allow/Block Rule with trusted/untrusted folder with wild card or trusted app name with wild card
/Applications/AppFolder/**/*.App
/Applications/AppFolder//Prefix*.App
3. Allow/Block Rule with wildcard on the 3rd level FQDNs :
*.google.com
*.facebook.com
*.intranet.local