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Echange server and MSME; 2179 error

Hi.

I received from xml log: <Data>TS: Operation has timed out.</Data> and I already googled it and found possible solution how to fix it, but there is one BUT!

The solutions looks like "Please disabe IP reputation" and I don't think that it cool idea. Because, I will disable a part of the important functionality.

I understood correctly, the problem is that MSME can't connect TrustedSource servers for differents problems? For example, firewall blocked the connections? 

Looking for any advices!:)

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