I trying to do a configuration for my scenario, let me describe for you:
I Have an Exchange server in my company and office 365 service too, some users out from exchange and other by office 365, and the office 365 is an alternate channel, like a failover, so, I configure my MEG for detect traffic outgoing for my schange server and office 365 IP, but some accounts doesn't through by MEG.
Looking in McAfee docummentation I found a article for use MEG or SaaS with office 365 but not with both (exchange + office 365).
Somebody has made this?
its possible, but we would need more details as to exactly what you are trying to do as the above is a bit vague. i recommend opening a case with support.