I am running DLP 10.0 on ePO 5.3. We have DLP to block all removable media and CD/DVD drives, using the default McAfee options. It works, testing with a CD will return an access denied, but it will not show the notification messages (that display for a couple seconds) in the bottom right, in the endpoint DLP section, nor in ePO. I was given a "fix" from a vendor to go in Device Manager and disable/enable the CD/DVD drive. When I do this, I get an immediate notification messages - in all three places. If I attempt to access the CD again, remove it and put in another one, there's no notification message. Each time I disable/enable the CD/DVD drive, notification messages appear. This is not a reliable method to log people that may be attempting to access the drives, it prevents them, but it doesn't tell me that they attempted it.
If I plug in a USB, I'll get an immediate notification message in all three locations.