@User67035436 this required depth troubleshooting by looking into the logs, please open a SR with support. However, couple of things.
1. ensure the DLPe version is latest.
2. No Fixed hard drive rule is created.
Yes in our case the issue was with the USB driver "Realtek USB 3.0 Card Reader" . Analyze the dump files and which should give the exact reason. Lenova T480s was coming with a old driver Realtek driver which crashed the system.
Log a call with McAfee, they can analyze the dump in more detail